|
|
chenodeoxycholoyl-CoA + glycine <=> H+ + glycochenodeoxycholic_acid + CoA
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
BMK
|
|
BRENDA:
BS321175
KEGG:
R08744
MetaCyc:
RXN-9851
SABIO-RK:
10196
|
|
|
|
chenodeoxycholoyl-CoA + taurine <=> H+ + taurochenodeoxycholate + CoA
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
BMK
|
|
BRENDA:
BS321176
KEGG:
R08745
MetaCyc:
RXN-9852
SABIO-RK:
10188
|
|
|
|
ATP + chenodeoxycholic_acid + CoA <=> AMP + diphosphate + chenodeoxycholoyl-CoA
|
6.2.1.7
cholate---CoA ligase
|
–
|
MK
|
|
BRENDA:
BS345
KEGG:
R08743
MetaCyc:
RXN-17398
|
|
|
|
chenodeoxycholoyl-CoA + H2O <=> chenodeoxycholic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.27
choloyl-CoA hydrolase
|
–
–
–
|
K
|
|
BRENDA:
BS360780
KEGG:
R03974
MetaCyc:
RXN-14289
SABIO-RK:
13309
|
|
|
|
propionyl-CoA + chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
|
not assigned
|
–
|
|
|
KEGG:
R04546
|
|
|
|
propionyl-CoA + chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA
|
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
|
K
|
|
KEGG:
R04811
|
|
|
|
chenodeoxycholoyl-CoA + NAD+ <=> choloyl-CoA + NADH + H+
|
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-17399
|
|
|
|
chenodeoxycholoyl-CoA + propionyl-CoA <=> 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestanoyl_CoA + CoA
|
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-9850
|
|
|
|
chenodeoxycholoyl-CoA + NAD+ <=> 3-oxo-chenodeoxycholy-CoA + NADH + H+
|
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
|
–
|
|
|
BRENDA:
BS437271
|
|
|
|
chenodeoxycholoyl-CoA + NADP+ <=> 3-oxochenodeoxycholoyl-CoA + NADPH + H+
|
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
|
–
|
|
|
BRENDA:
BS437270
|
|
|
|
lithocholoyl-CoA + chenodeoxycholic_acid <=> lithocholic_acid + chenodeoxycholoyl-CoA
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
|
BRENDA:
BS437675
|
|